On CentOS 5.4, installing php 5.3.3, is without mysqlnd
But is available mysql, mysqli, pdo_mysql
Installation
Installation on Unix
By default the MySQL database extensions are configured to use MySQL Client Library. In order to use the MySQL Native Driver, PHP needs to be built specifying that the MySQL database extensions are compiled with MySQL Native Driver support. This is done through configuration options prior to building the PHP source code.
For example, to build the MySQL extension, mysqli and PDO MYSQL using the MySQL Native Driver, the following command would be given:
./configure --with-mysql=mysqlnd \ --with-mysqli=mysqlnd \ --with-pdo-mysql=mysqlnd \ [other options]
Installation on Windows
In the official PHP distributions from 5.3 onwards, MySQL Native Driver is enabled by default, so no additional configuration is required to use it. All MySQL database extensions will use MySQL Native Driver in this case.
On ubuntu mysqlnd can be installed without source php code using synaptic package manager. However, phpmyadmin works I guess only with mysql, so if you use it you must keep an old driver.
After installing mysqlnd package you must restart apache in order new changes to take effect:
sudo service apache2 restart
or (if first doesn't work for you):
sudo /etc/init.d/apache2 restart
